A snow warning lasting almost two days could see communities cut off, while heavy rain and gale force winds are also due to bombard stormy Britain.
The Met Office’s snow warning covers much of the North from Wednesday morning lasting over 40 hours until 9pm on Thursday.
There is a “slight chance” some rural communities “could become cut off” amid the blizzard, while power cuts are also a possibility, the warning adds.
Weather charts also show wind gusts getting up to 40mph in parts of the country, while a rain warning is also in place across much of Northern Ireland from 3am tomorrow until 9am on Thursday.
It comes as forecasters continue to monitor developing conditions which could see another Beast from the East strike by February.
Freezing cold air moved in overnight causing temperatures in the north to plummet to negative double figures, while down south a separate weather front kept things much milder with highs of 9C.
Ice warnings issued yesterday afternoon run until 11am today across northern England and all of Scotland, with travel likely to be disrupted.
“A big contrast in temperatures and a big contrast in weather through Tuesday – rain and damp across much of England and Wales, certainly to start with,” said Met Office forecaster Alex Deakin.
“Across northern Britain plenty of sunshine but there is that ice risk in the morning – still some wintry showers moving in across the far north.”
He went on to say a fresh band of rain will begin to move in from tonight, becoming “quite a big player in our weather in the middle part of this week”.
“Pushing back eastwards during Tuesday evening, bringing some heavy rain to Northern Ireland on Wednesday and as it hits the polar air, we could start to see some heavy snowfall.”
Mr Deakin said the snow will initially fall over hills through Wednesday across northern England and southern Scotland, “but that band of wet weather persisting into Thursday when we could start to see snowfall totals building up”.
The weather front pushing east means by Thursday there will be a west to east temperature split, allowing for rain and milder temperatures in the likes of Belfast, Birmingham and the south west.
But it will be hovering just above zero in Norwich, Hull and Newcastle where the snow will strike hardest.